The Juxtaposition Cross of Control carries the same pair as the Left Angle Cross of Endeavor, Gate 21 and Gate 48. Human Design reads Gate 21, from Hexagram 21, Biting Through, sitting in the Heart or Will centre, as the will to control material life on one's own terms; and Gate 48, from Hexagram 48, The Well, sitting in the Spleen, as depth, a well of instinctive knowledge that is not yet useful, and a fear of being inadequate to what is asked. Juxtaposition Crosses stand apart from the other two families, tied only to the four line one profile, and are read as the most fixed direction the system names.
Its design half is Gate 54 and Gate 53, unchanged from the Cross of Endeavor, both seated in the Root. Gate 54 is read as ambition, the drive to rise and transform one's material circumstances; it pairs with Gate 32 in the channel of Transformation. Gate 53 is read as the pressure to begin, an impulse that often has no interest in seeing a thing through; it pairs with Gate 42 in the channel of Maturation.
Where the Left Angle reading holds this same will and depth as a role circumstance hands back, the Juxtaposition reading fixes it to the four line one profile instead, the same rising ambition and raw beginning beneath it either way. The same four gates also underlie the Juxtaposition Cross of Depth. The hexagrams are ancient; grouping them into one fixed cross is the modern system's own construction.