Where jing is dense essence and qi is functional energy, shen is the most refined of the Three Treasures, translated variously as "spirit," "mind" or "consciousness," and identified in the Huangdi Neijing with the vitality visible in a living person's eyes and countenance, a clinical sign practitioners still use to gauge a patient's underlying condition at a glance. Shen is said to be housed chiefly in the heart, called the jun huo, the sovereign fire or ruling organ, though the theory assigns each of the five zang organs its own resident aspect of spirit, the heart's shen alongside the liver's hun, the lungs' po, the spleen's yi and the kidneys' zhi, together forming the full picture of a person's mental and emotional life.
Disturbed shen is read from insomnia, disorientation, excessive dreaming, palpitations and, at its most severe, delirium or madness, conditions Chinese medicine has long treated through the same organ-based diagnostic framework rather than as a separate category of illness. Neidan, Daoist internal alchemy, treats the cultivation of shen as its final and highest stage, reached only after jing has been conserved and refined into qi and qi in turn refined into shen, at which point advanced practice aims to return shen to emptiness, reuniting it with the Dao.