Prepubertal Gynecomastia Linked to Lavender and Tea Tree Oils, Derek Henley and colleagues' 2007 article in the New England Journal of Medicine, reports a case series of three boys alongside laboratory evidence of estrogenic and antiandrogenic activity in lavender and tea tree oil. Its strength is publication in one of medicine's most rigorously vetted journals, combining clinical observation with supporting laboratory data. Its limit is that later industry funded reanalyses disputed the causal strength that can be drawn from a small case series of three patients, a limitation this atlas states alongside the finding rather than presenting it as beyond question.
Facts
Assessment
Reliability Tier1
Derek Henley and colleagues' 2007 article in the New England Journal of Medicine, the top tier reflecting publication in one of medicine's most rigorously vetted journals, combining clinical observation with supporting laboratory data. Its limit is that later industry funded reanalyses disputed the causal strength that can be drawn from a small case series of three patients, a limitation stated alongside the finding rather than presented as beyond question. NotesCase series of three boys plus in vitro evidence of estrogenic/antiandrogenic activity in lavender and tea tree oil; later industry-funded reanalyses disputed the causal strength of the small case series.
Citation
AuthorDerek Henley et al.
PublisherNew England Journal of Medicine
Publication Year2007
Source Typepeer-reviewed article
Claims Backed By This Source (10 claims)
This source backs 10 claims across the atlas. As facts: 8 well-attested, 1 scholarly debate. Plus 1 entities citing it as a general reference with no single fact or relationship attached.
Disposition By Topic
- Sources, 7 claims: 7 well-attested.
- Disciplines, 2 claims: 1 scholarly debate, 1 general references.
- Articles, 1 claims: 1 well-attested.
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