Genesis never explains why Cain's offering was refused, and that gap has generated centuries of commentary rather than closing it. Rabbinic tradition, collected in Genesis Rabbah, debates whether the fault lay in the offering itself, in Cain's inward state, or in an unstated failure to bring his very best, and wrestles with why God, who already knows everything, asks Cain where his brother is at all; the usual answer is that the question invites confession rather than supplies information God lacks.
The New Testament uses Cain as a fixed moral marker: the First Letter of John contrasts loving one another with Cain, "who belonged to the evil one and murdered his brother," and the Letter of Jude condemns those who have gone "the way of Cain." The Quran tells a parallel story of Adam's two sons without naming either, adding a detail absent from Genesis: after the murder, Cain does not know how to dispose of the body until he watches a raven scratch at the ground to bury another raven, and learns from it. Later Islamic commentary supplies the names Qabil and Habil, absent from the Quranic text itself.
A minority current ran the other way. Irenaeus of Lyons reports a second century group, the Cainites, who read Cain, Esau, Korah and Judas as recipients of hidden knowledge the Genesis narrator suppressed, inverting the ordinary moral reading point for point. Nothing survives in the group's own words, so what is known comes only through a hostile source written to refute it. The phrase "mark of Cain" outlived the argument over what the mark was, becoming an English idiom for a stigma of guilt, and Byron's 1821 drama Cain, A Mystery recast the fratricide as a rebel against an arbitrary God.