Jason is sent for the Golden Fleece by a usurping uncle who expects the errand to kill him. He has a ship built, the Argo, and assembles a crew that reads like a catalogue of the previous generation of heroes: Heracles for a while, Orpheus to keep the rowing in time and to out-sing the Sirens, Castor and Pollux, Atalanta in some versions, and a long list of names whose local traditions the poets were tying together.
The voyage is a sequence of set pieces, and the geography is a map of the edge of the known world as it looked to early Greek sailors of the Black Sea: clashing rocks that crush ships between them, a blind seer tormented by Harpies, a king with a savage boxing habit, women who have killed all their men. It is the oldest of the Greek quest narratives and probably older than the Trojan material, and Homer refers to it as a story his audience already knows.
At Colchis, at the far eastern end of the sea, the king sets three impossible tasks. Jason performs all three and none of them by his own resources: Medea, the king's daughter, a priestess of Hecate and granddaughter of the Sun, gives him a drug against fire, tells him how to defeat the sown men, and finally puts the sleepless serpent to sleep herself.