Cassian spent years in the Egyptian desert with his friend Germanus, first at Bethlehem and then among the monks of Scetis, at the period when that community was at its height. He left during the Origenist troubles, went to Constantinople, where he was ordained by John Chrysostom, and eventually settled at Marseilles, where he founded a monastery for men and one for women and wrote the two books he is known for.
The Institutes is the practical one: how a monastery is to be arranged, what the monks wear, how the offices are ordered, and then a treatment of the eight principal faults. The Conferences is the interior one, twenty four dialogues in which he and Germanus put questions to named elders of the desert and receive extended answers on discernment, on prayer, on friendship, on the purpose of the whole enterprise.
What he is actually transmitting, in the analysis of the faults and in the account of prayer, is very largely the psychology of Evagrius, whom he had known in Egypt and whom he never once names. That silence is not carelessness. Evagrius was under a cloud by the time Cassian wrote, and naming him would have discredited the material. The result is that the Latin West received the desert's interior science in a form its author could not be credited for, and read it for a thousand years.