Ptolemy assigns the Pleiades as a group the nature of the Moon and Mars, and Alcyone inherits that attribution as the cluster's brightest member. Robson and later compilers write it up under Alcyone's own name, which slightly obscures the fact that the assignment was originally to the cluster.
The delineation is unusually consistent and unusually unpleasant: blindness and eye trouble, weeping, sorrow, disgrace, violence, and eminence achieved through difficulty. The eye connection is worth explaining because it is systematic rather than arbitrary. Ptolemy and the tradition after him treat nebulous objects, clusters and what were taken to be cloudy patches, as affecting the eyesight, on a straightforward analogy: a blurred object in the sky signifies blurred vision. The same reasoning attaches eye trouble to Praesepe in Cancer and to other nebulous positions. It is a consistent rule, applied across the catalogue, and it is a signature argument of exactly the kind found throughout this material.
The weeping association has a separate and older root. The Pleiades are the seven daughters of Atlas, and in several tellings they are grieving: for their father's burden, or for their sisters the Hyades, whose name was connected in antiquity with rain. Rain, tears and the cluster's seasonal rising are bound together in Greek material and independently in other traditions.
Alcyone is one of Agrippa's Behenian fifteen, paired with rock crystal and with fennel.
The Pleiades' heliacal rising and setting were agricultural markers across the ancient world, Hesiod's Works and Days uses them to time ploughing and harvest, and the cluster is significant in Japanese, Maori, Aboriginal Australian and Mesoamerican traditions independently.